Shadowforge does not support drawing with 2 pixels using draw tiled (pixel perfect) over a large canvas such as 1920x1080. But here's the catch.
You can draw your prop or character in a larger canvas and then resize it. After you've resized it, since Shadowforge is not exclusively a pixel art software, you can draw smoothly and you can smudge.
Here's an alien character I painted. I first painted it with large pixels. Then I resized it and started to smudge it to make it look dithered. If you want it crispy, then you can still have it crispy. But I preferred to make it dithered. And this is the result.
From this.

To this.

Now if you want to go further you can make it look human and animate it.
